Vol. 2, 2017

Original research papers

Biomedicine

ELECTROMAGNETIC FIELD THERAPY AND IMMUNE MECHANISMS WHICH ARE INVOLVED IN ANTI-INFLAMMATORY RESPONSE

Mihai Surcel, Didi Surcel, Sebastian Toader, Mioara Butan

Pages: 243-248

DOI: 10.21175/RadProc.2017.50

The aim of this study was to evaluate the mechanism by which EMF therapy can interfere with the modified immune and oxidative reactions by the experimental approach on the lab animals. In vivo and vitro experiment was carried out on 60 Wistar rats that were divided in 4 groups as following: 1. Control-group tested on the 10th day; 2.ELF-EMF-exposed group tested on the 10th day; 3. Group that received intradermic Staphylococcus aureus culture (SA) and was tested on the 10th day; 4. Group that received intradermic SA and was treated with ELF- EMF and was tested after 10 days. The rats were exposed to 50 Hz, 1 mT. Splenic lymphocytes and alveolar macrophages for the cellular cultures were harvested. The following parameters were assessed: a) 3HTdR incorporation test; b) Macrophage inhibition factor (MIF) assay; c)Inteleukine-1 (IL-1)-assay; d) Tumor Necrosis Factor (TNF)- assay; e) Chemiluminescence assay; f) Phagocytosis assay. The 3HTdR incorporation assay and assays for cytokine activity and phagocytosis indicate a partial reversal of the values of the results obtained in the ELF + EMF group. Our experiment reveals that the EMF interferes with the immune and oxidative systems, becomes chronic and plays a key role in the development of serious diseases. The EMF-therapy can be beneficial in reducing the inflammation by interfering with the inflammatory molecules and surface receptors.
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