he aim of the study is to assess the role of the surgical technique and liver response in the development of complications after transcatheter arterial chemoembolization of liver arteries using drug-eluting beads (DEB-TACE). The study included 34 patients who underwent 52 DEB-TACE with drug-saturated microspheres in 2014 - 2020. CT and MRI were performed for follow-up and if complications were suspected. The modification of the surgical technique made it possible to avoid complications from the vascular wall and non-target embolization. Stages of complications from the bile ducts can be diagnosed on CT and MRI. This can help slow down the further development of the process. Separate patients at risk groups based on previous treatment prevent of developing severe complications.

1. R.J. Lewandowski, M.F. Mulcahy, L.M. Kulik et al. “Chemoembolization for Hepatocellular Carcinoma” Radiology, vol. 255, no. 3, pp. 955-965, Jun. 2010.
   DOI: 10.1148/radiol.10091473
   PMiD: 20501733
2. N. Kennoki, T. Saguchi, T. Sano, Y. Takara, T. Moriya et al. “Long-term Histopathologic Follow-up of a Spherical Embolic Agent; Observation of the Transvascular Migration of HepaSphere^TM”, BJR Case Rep, Jun 25 (5), 1, 20180066, 2019.
   DOI: 10.1259/bjrcr.20180066
3. Y. Xiao-Dan, Y. Zuguo, Z. Hang et al. “Radiological biomarkers for assessing response to locoregional therapies in hepatocellular carcinoma: From morphological to functional imaging”, Oncology reports, vol. 37, no. 3, pp. 1337-1346, 2017.
   DOI: 10.3892/or.2017.5420
4. J. Chung, J-S. Yu, J. H. Kim et al. “Haemodynamic events and localised parenchymal changes following transcatheter arterial chemoembolisation for hepatic malignancy: interpretation of imaging findings”. The British Journal of Radiology, no. 83, pp. 71–81, 2010.
   DOI: 10.3892/mco.2017.1235
5. А.М. Бабунашвили, Д.П. Дундуа, З.А. Кавтеладзе, Д.С. Карташов, Переход с трансбедренного на трансрадиальный доступ в практике интервенционной кардиологии: сможет ли стать трансрадиальный доступ методом выбора? // Международный журнал интервенционной кардиоангиологии, ― 2005, ― №7, ― С. 73. [A.M. Babunashvili, D.P. Dundua, Z.A. Kavteladze, D.S. Kartashov, The transition from transfemoral to transradial access in the practice of interventional cardiology: can transradial access be the method of choice? // International Journal of Interventional Cardioangiology, 2005 (7):73. (In Russian)]
6. S. Chittapuram, B. Ramesh, S. Malay, “Biliary Tract Anatomy and its Relationship with Venous Drainage”, Journal of Clinical and Experimental Hepatology, no. 1, pp. 18–26, 2014.
   DOI: 10.1016/j.jceh.2013.05.002
   PMCid: PMC4244820
7. B. Guiu et al. “Liver/biliary injuries following chemoembolisation of endocrine tumours and hepatocellular carcinoma: Lipiodol vs. drug-eluting beads”. Journal of hepatology, vol. 56, no 3, pp. 609–617, 2012.
   DOI: 10.1016/j.jhep.2011.09.012
   PMiD: 22027582
8. J. C. Spina, M. Ulla, E.L. Yeyati, M.C. Kucharczyk, H. Irusta, J.L. Savluk et al. “MDCT findings after hepatic chemoembolization with DC-beads: What the radiologist needs to know”, Abdominal Imaging, vol. 38, pp. 778–784, 2013.
   DOI: 10.1007/s00261-012-9963-6

Elena Zvezdkina, Dmitry Lebedev, Anna Kedrova, Yulia Stepanova, Dmitry Astakhov, Dmitry Panchenkov, "Multidisciplinary approach in the prevention and treatment of complications of transcatheter arterial chemoembolization of liver arteries,", RAD Conf. Proc, vol. 4, 2020, pp. 66–68, http://doi.org/10.21175/RadProc.2020.13